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PortableApps.com offers a collection of programs specifically configured to run from portable USB devices like pen drives, external hard drives, and MP3 players.
The PortableApps.com Standard Suite includes:

Mozilla Firefox Portable Edition (web browser)
Mozilla Sunbird Portable Edition (calendar/task manager)
Mozilla Thunderbird Portable Edition (email client)
OpenOffice.org Portable (office suite compatible with Microsoft Word files)